Cell & Tissue Morphology
A fully PC controlled FE SEM intended for both – for high vacuum as well as for low vacuum operations. Outstanding optical properties, flicker-free...
Cell membrane functions as a protection layer to the intracellular environment and together with cytoskeleton defines the outer shape of a cell. In addition to its structural role, the membrane is also a place where many important events occur, such as cell differentiation, signaling and interactions with extracellular space. Changes in the morphology of the outer membrane can be an evidence of altered cellular functions, such as tumor formation, viral attack or stem cell differentiation. TESCAN SEMs are ideal instruments for investigating cellular and tissue structure with high resolution. Applications involve investigations of cell-pathogen interactions or investigating morphological changes in response to the changes in the extracellular environment. Our UHR SEMs are specifically designed for ultrahigh resolution imaging at low accelerating voltages, thus providing the best topographic contrast and resolution. This helps scientists investigate shape changes of grooves, pores, blebs or microvilli on the cellular surface. Non-coated and highly charging samples can be observed in the variable pressure mode under non-dehydrating conditions.
Morphology assessment of fibroblast growth. Conditions: 10 kV, SE detector.